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Efficient Gene Editing through Direct Cytosolic Delivery of CRISPR/Cas9-Ribonucleoprotein

Genome editing through the delivery of CRISPR/Cas9-ribonulceoprotein (Cas9-RNP) reduces unwanted gene targeting and avoids integrational mutagenesis that can occur through gene delivery strategies. Direct and efficient delivery of Cas9-RNP into the cytosol followed by translocation to the nucleus re...

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Bibliografske podrobnosti
izdano v:ACS Nano
Main Authors: Mout, Rubul, Ray, Moumita, Tonga, Gulen Yesilbag, Lee, Yi-Wei, Tay, Tristan, Sasaki, Kanae, Rotello, Vincent M.
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5848212/
https://ncbi.nlm.nih.gov/pubmed/28129503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsnano.6b07600
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