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In Vivo Delivery of CRISPR/Cas9 for Therapeutic Gene Editing: Progress and Challenges

The successful use of CRISPR/Cas9 based gene editing for therapeutics requires efficient in vivo delivery of the CRISPR components. There are, however, major challenges on the delivery front. In this Topical Review, we will highlight recent developments in CRISPR delivery, and we will present hurdle...

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Bibliografiska uppgifter
I publikationen:Bioconjug Chem
Huvudupphovsmän: Mout, Rubul, Ray, Moumita, Lee, Yi-Wei, Scaletti, Federica, Rotello, Vincent M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2017
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5846329/
https://ncbi.nlm.nih.gov/pubmed/28263568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.bioconjchem.7b00057
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