Role of angiopoietin-like 3 (ANGPTL3) in regulating plasma level of low-density lipoproteins

BACKGROUND AND AIMS: Angiopoietin-like 3 (ANGPTL3) has emerged as a key regulator of lipoprotein metabolism in humans. Homozygous loss of ANGPTL3 function causes familial combined hypolipidemia characterized by low plasma levels of triglycerides (TG), high-density lipoprotein cholesterol (HDL-C), an...

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Detalhes bibliográficos
Publicado no:Atherosclerosis
Main Authors: Xu, Yu-Xin, Redon, Valeska, Yu, Haojie, Querbes, William, Pirruccello, James, Liebow, Abigail, Deik, Amy, Trindade, Kevin, Wang, Xiao, Musunuru, Kiran, Clish, Clary B., Cowan, Chad, Fizgerald, Kevin, Rader, Daniel, Kathiresan, Sekar
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5750127/
https://ncbi.nlm.nih.gov/pubmed/29183623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.atherosclerosis.2017.08.031
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