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Angiopoietin-Like 3: From Discovery to Therapeutic Gene Editing
Hyperlipidemia is a major causal risk factor for atherosclerosis and coronary heart disease (CHD). Angiopoietin-like 3 (ANGPTL3) has emerged as a promising molecular target to reduce CHD risk due to its regulation of all 3 major lipid traits: low-density lipoprotein cholesterol, high-density lipopro...
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| Veröffentlicht in: | JACC Basic Transl Sci |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Elsevier
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6834959/ https://ncbi.nlm.nih.gov/pubmed/31709322 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacbts.2019.05.008 |
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