Control of cellular homeostasis: organelles take the pilot's seat

Yazar: Tooze, Sharon, Zoncu, Roberto
Yayımlandı Mol Biol Cell (2015)

Cell Biology: the TASCC of secretion

Yazar: Zoncu, Roberto, Sabatini, David M.
Baskı/Yayın Bilgisi 2011

The lysosome as a command-and-control center for cellular metabolism

Yazar: Lim, Chun-Yan, Zoncu, Roberto
Yayımlandı J Cell Biol (2016)

Emerging roles for the lysosome in lipid metabolism

Yazar: Thelen, Ashley M., Zoncu, Roberto
Yayımlandı Trends Cell Biol (2017)

The Lysosome at the intersection of cellular growth and destruction.

Yazar: Shin, Hijai R., Zoncu, Roberto
Yayımlandı Dev Cell (2020)

Amino acids and mTORC1: from lysosomes to disease

Yazar: Efeyan, Alejo, Zoncu, Roberto, Sabatini, David M.
Baskı/Yayın Bilgisi 2012

mTOR: from growth signal integration to cancer, diabetes and ageing

Yazar: Zoncu, Roberto, Sabatini, David M., Efeyan, Alejo
Baskı/Yayın Bilgisi 2010

Defective regulation of autophagy upon leucine deprivation reveals a targetable liability of human melanoma cells in vitro and in vivo

Yazar: Sheen, Joon-Ho, Zoncu, Roberto, Kim, Dohoon, Sabatini, David M.
Baskı/Yayın Bilgisi 2011

An expanded Ragulator is a GEF for the Rag GTPases that signal amino acid levels to mTORC1

Yazar: Bar-Peled, Liron, Schweitzer, Lawrence D., Zoncu, Roberto, Sabatini, David M.
Baskı/Yayın Bilgisi 2012

Two synaptojanin 1 isoforms are recruited to clathrin-coated pits at different stages

Yazar: Perera, Rushika M., Zoncu, Roberto, Lucast, Louise, De Camilli, Pietro, Toomre, Derek
Baskı/Yayın Bilgisi 2006

Dynamics and architecture of the NRBF2-containing phosphatidylinositol 3-kinase complex I of autophagy

Yazar: Young, Lindsey N., Cho, Kelvin, Lawrence, Rosalie, Zoncu, Roberto, Hurley, James H.
Yayımlandı Proc Natl Acad Sci U S A (2016)

mTORC1 senses lysosomal amino acids through an inside-out mechanism that requires the Vacuolar H(+)-ATPase

Yazar: Zoncu, Roberto, Bar-Peled, Liron, Efeyan, Alejo, Wang, Shuyu, Sancak, Yasemin, Sabatini, David M.
Baskı/Yayın Bilgisi 2011

Identification of an Oncogenic RAB Protein

Yazar: Wheeler, Douglas B., Zoncu, Roberto, Root, David E., Sabatini, David M., Sawyers, Charles L.
Yayımlandı Science (2015)

A phosphoinositide switch controls the maturation and signaling properties of APPL endosomes

Yazar: Zoncu, Roberto, Perera, Rushika M, Balkin, Daniel M, Pirruccello, Michelle, Toomre, Derek, De Camilli, Pietro
Baskı/Yayın Bilgisi 2009

Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids

Yazar: Sancak, Yasemin, Bar-Peled, Liron, Zoncu, Roberto, Markhard, Andrew L., Nada, Shigeyuki, Sabatini, David M.
Baskı/Yayın Bilgisi 2010

NBEAL1 controls SREBP2 processing and cholesterol metabolism and is a susceptibility locus for coronary artery disease

Yazar: Bindesbøll, Christian, Aas, Aleksander, Ogmundsdottir, Margret Helga, Pankiv, Serhiy, Reine, Trine, Zoncu, Roberto, Simonsen, Anne
Yayımlandı Sci Rep (2020)

Dynamics of mTORC1 activation in response to amino acids

Yazar: Manifava, Maria, Smith, Matthew, Rotondo, Sergio, Walker, Simon, Niewczas, Izabella, Zoncu, Roberto, Clark, Jonathan, Ktistakis, Nicholas T
Yayımlandı eLife (2016)

PhotoGate microscopy to track single molecules in crowded environments

Yazar: Belyy, Vladislav, Shih, Sheng-Min, Bandaria, Jigar, Huang, Yongjian, Lawrence, Rosalie E., Zoncu, Roberto, Yildiz, Ahmet
Yayımlandı Nat Commun (2017)

The inositol 5-phosphatase SHIP2 regulates endocytic clathrin-coated pit dynamics

Yazar: Nakatsu, Fubito, Perera, Rushika M., Lucast, Louise, Zoncu, Roberto, Domin, Jan, Gertler, Frank B., Toomre, Derek, De Camilli, Pietro
Baskı/Yayın Bilgisi 2010

The Folliculin tumor suppressor is a GAP for RagC/D GTPases that signal amino acid levels to mTORC1

Yazar: Tsun, Zhi-Yang, Bar-Peled, Liron, Chantranupong, Lynne, Zoncu, Roberto, Wang, Tim, Kim, Choah, Spooner, Eric, Sabatini, David M.
Baskı/Yayın Bilgisi 2013