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A phosphoinositide switch controls the maturation and signaling properties of APPL endosomes

The recent identification of several novel endocytic compartments has challenged our current understanding of the topological and functional organization of the endocytic pathway. Using quantitative single vesicle imaging and acute manipulation of phosphoinositides we show that APPL endosomes, which...

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Autori principali: Zoncu, Roberto, Perera, Rushika M, Balkin, Daniel M, Pirruccello, Michelle, Toomre, Derek, De Camilli, Pietro
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2705806/
https://ncbi.nlm.nih.gov/pubmed/19303853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2009.01.032
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