Loss of endocytic clathrin-coated pits upon acute depletion of phosphatidylinositol 4,5-bisphosphate

Phosphatidylinositol 4,5-bisphosphate [PI(4,5)P(2)], a phosphoinositide concentrated predominantly in the plasma membrane, binds endocytic clathrin adaptors, many of their accessory factors, and a variety of actin-regulatory proteins. Here we have used fluorescent fusion proteins and total internal...

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Detalhes bibliográficos
Main Authors: Zoncu, Roberto, Perera, Rushika M., Sebastian, Rafael, Nakatsu, Fubito, Chen, Hong, Balla, Tamas, Ayala, Guillermo, Toomre, Derek, De Camilli, Pietro V.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1805489/
https://ncbi.nlm.nih.gov/pubmed/17360432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0611733104
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