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Phosphatidylinositol-(4,5)-bisphosphate regulates clathrin-coated pit initiation, stabilization, and size

Clathrin-mediated endocytosis (CME) is the major mechanism for internalization in mammalian cells. CME initiates by recruitment of adaptors and clathrin to form clathrin-coated pits (CCPs). Nearly half of nascent CCPs abort, whereas others are stabilized by unknown mechanisms and undergo further mat...

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Bibliografiske detaljer
Main Authors: Antonescu, Costin N., Aguet, François, Danuser, Gaudenz, Schmid, Sandra L.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Cell Biology 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3135483/
https://ncbi.nlm.nih.gov/pubmed/21613550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E11-04-0362
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