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A phosphoinositide switch controls the maturation and signaling properties of APPL endosomes

The recent identification of several novel endocytic compartments has challenged our current understanding of the topological and functional organization of the endocytic pathway. Using quantitative single vesicle imaging and acute manipulation of phosphoinositides we show that APPL endosomes, which...

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Detalhes bibliográficos
Main Authors: Zoncu, Roberto, Perera, Rushika M, Balkin, Daniel M, Pirruccello, Michelle, Toomre, Derek, De Camilli, Pietro
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2705806/
https://ncbi.nlm.nih.gov/pubmed/19303853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2009.01.032
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