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Amino acids and mTORC1: from lysosomes to disease

The mechanistic target of rapamycin (mTOR) kinase controls growth and metabolism, and its deregulation underlies the pathogenesis of many diseases, including cancer, neurodegeneration, and diabetes. mTOR complex 1 (mTORC1) integrates signals arising from nutrients, energy, and growth factors, but ho...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Efeyan, Alejo, Zoncu, Roberto, Sabatini, David M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3432651/
https://ncbi.nlm.nih.gov/pubmed/22749019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmed.2012.05.007
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