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Amino acids and mTORC1: from lysosomes to disease
The mechanistic target of rapamycin (mTOR) kinase controls growth and metabolism, and its deregulation underlies the pathogenesis of many diseases, including cancer, neurodegeneration, and diabetes. mTOR complex 1 (mTORC1) integrates signals arising from nutrients, energy, and growth factors, but ho...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3432651/ https://ncbi.nlm.nih.gov/pubmed/22749019 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmed.2012.05.007 |
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