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Amino acids and mTORC1: from lysosomes to disease

The mechanistic target of rapamycin (mTOR) kinase controls growth and metabolism, and its deregulation underlies the pathogenesis of many diseases, including cancer, neurodegeneration, and diabetes. mTOR complex 1 (mTORC1) integrates signals arising from nutrients, energy, and growth factors, but ho...

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Bibliografski detalji
Glavni autori: Efeyan, Alejo, Zoncu, Roberto, Sabatini, David M.
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3432651/
https://ncbi.nlm.nih.gov/pubmed/22749019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmed.2012.05.007
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