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Nutrients versus growth factors in mTORC1 activation

Growth factors and nutrients regulate the mechanistic target of rapamycin complex 1 (mTORC1) by different mechanisms. The players that link growth factors and mTORC1 activation have been known for several years and mouse models have validated its relevance for human physiology and disease. In contra...

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Detalhes bibliográficos
Main Authors: Efeyan, Alejo, Sabatini, David M
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3845370/
https://ncbi.nlm.nih.gov/pubmed/23863153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BST20130063
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