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Nutrient mTORC1 signaling underpins regulatory T cell control of immune tolerance
Foxp3(+) regulatory T (T reg) cells are pivotal regulators of immune tolerance, with T cell receptor (TCR)–driven activated T reg (aT reg) cells playing a central role; yet how TCR signaling propagates to control aT reg cell responses remains poorly understood. Here we show that TCR signaling induce...
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| 出版年: | J Exp Med |
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| 主要な著者: | , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Rockefeller University Press
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7037250/ https://ncbi.nlm.nih.gov/pubmed/31649036 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20190848 |
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