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Dynamics and architecture of the NRBF2-containing phosphatidylinositol 3-kinase complex I of autophagy
The class III phosphatidylinositol 3-kinase complex I (PI3KC3-C1) is central to autophagy initiation. We previously reported the V-shaped architecture of the four-subunit version of PI3KC3-C1 consisting of VPS (vacuolar protein sorting) 34, VPS15, BECN1 (Beclin 1), and ATG (autophagy-related) 14. He...
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| Publicado en: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4961193/ https://ncbi.nlm.nih.gov/pubmed/27385829 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1603650113 |
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