α5β1 Integrin Activates an NF-κB-Dependent Program of Gene Expression Important for Angiogenesis and Inflammation

GeneCalling, a genome-wide method of mRNA profiling, reveals that endothelial cells adhering to fibronectin through the α5β1 integrin, but not to laminin through the α2β1 integrin, undergo a complex program of gene expression. Several of the genes identified are regulated by the NF-κB transcription...

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Detalhes bibliográficos
Main Authors: Klein, Sharon, de Fougerolles, Antonin R., Blaikie, Pamela, Khan, Leila, Pepe, Angela, Green, Cynthia D., Koteliansky, Victor, Giancotti, Filippo G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Cell Growth and Development
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC133962/
https://ncbi.nlm.nih.gov/pubmed/12138201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.16.5912-5922.2002
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