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Lipid nanoparticles for targeted siRNA delivery – going from bench to bedside

This review covers the basic aspects of small interfering RNA delivery by lipid nano-particles (LNPs) and elaborates on the current status of clinical trials for these systems. We briefly describe the roles of all LNP components and possible strategies for their improvement. We also focus on the cur...

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Bibliografske podrobnosti
izdano v:Int J Nanomedicine
Main Authors: Zatsepin, Timofei S, Kotelevtsev, Yuri V, Koteliansky, Victor
Format: Artigo
Jezik:Inglês
Izdano: Dove Medical Press 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4939975/
https://ncbi.nlm.nih.gov/pubmed/27462152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S106625
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