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Lipid nanoparticles for targeted siRNA delivery – going from bench to bedside

This review covers the basic aspects of small interfering RNA delivery by lipid nano-particles (LNPs) and elaborates on the current status of clinical trials for these systems. We briefly describe the roles of all LNP components and possible strategies for their improvement. We also focus on the cur...

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Detalhes bibliográficos
Publicado no:Int J Nanomedicine
Main Authors: Zatsepin, Timofei S, Kotelevtsev, Yuri V, Koteliansky, Victor
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4939975/
https://ncbi.nlm.nih.gov/pubmed/27462152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S106625
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