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Both early and delayed anti-CD40L antibody treatment induces a stable plaque phenotype

In the present study, we investigated the role of the CD40L-CD40 pathway in a model of progressive atherosclerosis. ApoE−/− mice were treated with an anti-CD40L antibody or a control antibody for 12 wk. Antibody treatment started early (age 5 wk) or was delayed until after the establishment of ather...

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Detalhes bibliográficos
Main Authors: Lutgens, Esther, Cleutjens, Kitty B. J. M., Heeneman, Sylvia, Koteliansky, Victor E., Burkly, Linda C., Daemen, Mat J. A. P.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC16568/
https://ncbi.nlm.nih.gov/pubmed/10861013
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