The CD40-TRAF6 axis is the key regulator of the CD40/CD40L system in neointima formation and arterial remodeling

We investigated the role of CD40 and CD40L in neointima formation and identified the downstream CD40-signaling intermediates (tumor necrosis factor [TNF]–receptor associated factors [TRAF]) involved. Neointima formation was induced in wild-type, CD40(−/−), CD40L(−/−), and in CD40(−/−) mice that cont...

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Vydáno v:Blood
Hlavní autoři: Donners, Marjo M. P. C., Beckers, Linda, Lievens, Dirk, Munnix, Imke, Heemskerk, Johan, Janssen, Ben J., Wijnands, Erwin, Cleutjens, Jack, Zernecke, Alma, Weber, Christian, Ahonen, Cory L., Benbow, Ulrike, Newby, Andrew C., Noelle, Randolph J., Daemen, Mat J. A. P., Lutgens, Esther
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2008
Témata:
Hemostasis, Thrombosis, and Vascular Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5726330/
https://ncbi.nlm.nih.gov/pubmed/18195092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-05-088906
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