Proinflammatory Responses Induced by CD40 in Retinal Endothelial and Müller Cells are Inhibited by Blocking CD40-Traf2,3 or CD40-Traf6 Signaling

PURPOSE. The cell surface receptor CD40 is required for the development of retinopathies induced by diabetes and ischemia/reperfusion. The purpose of this study was to identify signaling pathways by which CD40 triggers proinflammatory responses in retinal cells, since this may lead to pharmacologic...

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Publicat a:Invest Ophthalmol Vis Sci
Autors principals: Portillo, Jose-Andres C., Schwartz, Isaac, Zarini, Simona, Bapputty, Reena, Kern, Timothy S., Gubitosi-Klug, Rose A., Murphy, Robert C., Subauste, M. Cecilia, Subauste, Carlos S.
Format: Artigo
Idioma:Inglês
Publicat: The Association for Research in Vision and Ophthalmology 2014
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4280881/
https://ncbi.nlm.nih.gov/pubmed/25477319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.14-15340
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