Blockade of CD40–TRAF2,3 or CD40–TRAF6 is sufficient to inhibit pro-inflammatory responses in non-haematopoietic cells

Inhibition of the CD40–CD154 pathway controls inflammatory disorders. Unfortunately, administration of anti-CD154 monoclonal antibodies causes thromboembolism. Blockade of signalling downstream of CD40 may represent an approach to treat CD40-driven inflammatory disorders. Blocking tumour necrosis fa...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Immunology
Main Authors: Portillo, Jose-Andres C, Greene, Jennifer A, Schwartz, Isaac, Subauste, Maria Cecilia, Subauste, Carlos S
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2015
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4264907/
https://ncbi.nlm.nih.gov/pubmed/25051892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12361
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados