The CD40-TRAF6 axis is the key regulator of the CD40/CD40L system in neointima formation and arterial remodeling

We investigated the role of CD40 and CD40L in neointima formation and identified the downstream CD40-signaling intermediates (tumor necrosis factor [TNF]–receptor associated factors [TRAF]) involved. Neointima formation was induced in wild-type, CD40(−/−), CD40L(−/−), and in CD40(−/−) mice that cont...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Donners, Marjo M. P. C., Beckers, Linda, Lievens, Dirk, Munnix, Imke, Heemskerk, Johan, Janssen, Ben J., Wijnands, Erwin, Cleutjens, Jack, Zernecke, Alma, Weber, Christian, Ahonen, Cory L., Benbow, Ulrike, Newby, Andrew C., Noelle, Randolph J., Daemen, Mat J. A. P., Lutgens, Esther
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2008
Assuntos:
Hemostasis, Thrombosis, and Vascular Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5726330/
https://ncbi.nlm.nih.gov/pubmed/18195092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-05-088906
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