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Impact of Self-Assembly Properties on Antibacterial Activity of Short Acyl-Lysine Oligomers
We investigated both the structural and functional consequences of modifying the hydrophobic, lipopeptide-mimetic oligo-acyl-lysine (OAK) N(α)-hexadecanoyl-l-lysyl-l-lysyl-aminododecanoyl-l-lysyl-amide (c(16)KKc(12)K) to its unsaturated analog hexadecenoyl-KKc(12)K [c(16(ω7))KKc(12)K]. Despite simil...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2592853/ https://ncbi.nlm.nih.gov/pubmed/18838600 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00656-08 |
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