Macrophage Notch ligand Delta-like 4 promotes vein graft lesion development: implications for the treatment of vein graft failure

OBJECTIVE: Despite its large clinical impact, the underlying mechanisms for vein graft failure remain obscure and no effective therapeutic solutions are available. We tested the hypothesis that Notch signaling promotes vein graft disease. APPROACH AND RESULTS: We used two biotherapeutics for Delta-l...

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Gepubliceerd in:Arterioscler Thromb Vasc Biol
Hoofdauteurs: Koga, Jun-ichiro, Nakano, Toshiaki, Dahlman, James E., Figueiredo, Jose-Luiz, Zhang, Hengmin, Decano, Julius, Khan, Omar F, Niida, Tomiharu, Iwata, Hiroshi, Aster, Jon C., Yagita, Hideo, Anderson, Daniel G., Ozaki, C. Keith, Aikawa, Masanori
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5003117/
https://ncbi.nlm.nih.gov/pubmed/26404485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.115.305516
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