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Alkane-modified short polyethyleneimine for siRNA delivery

RNA interference (RNAi) is a highly specific gene-silencing mechanism triggered by small interfering RNA (siRNA). Effective intracellular delivery requires the development of potent siRNA carriers. Here, we describe the synthesis and screening of a series of siRNA delivery materials. Short polyethyl...

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Detalhes bibliográficos
Main Authors: Schroeder, Avi, Dahlman, James E., Sahay, Gaurav, Love, Kevin T., Jiang, Shan, Eltoukhy, Ahmed A., Levins, Christopher G., Wang, Yingxia, Anderson, Daniel G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3814168/
https://ncbi.nlm.nih.gov/pubmed/22155553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2011.11.030
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