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Lipidoid-coated Iron Oxide Nanoparticles for Efficient DNA and siRNA delivery

The safe, targeted and effective delivery of gene therapeutics remains a significant barrier to their broad clinical application. Here we develop a magnetic nucleic acid delivery system composed of iron oxide nanoparticles and cationic lipid-like materials termed lipidoids. Coated nanoparticles are...

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Détails bibliographiques
Auteurs principaux: Jiang, Shan, Eltoukhy, Ahmed A., Love, Kevin T., Langer, Robert, Anderson, Daniel G.
Format: Artigo
Langue:Inglês
Publié: 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3992974/
https://ncbi.nlm.nih.gov/pubmed/23394319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nl304287a
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