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Anti–microRNA-21 oligonucleotides prevent Alport nephropathy progression by stimulating metabolic pathways
MicroRNA-21 (miR-21) contributes to the pathogenesis of fibrogenic diseases in multiple organs, including the kidneys, potentially by silencing metabolic pathways that are critical for cellular ATP generation, ROS production, and inflammatory signaling. Here, we developed highly specific oligonucleo...
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| 發表在: | J Clin Invest |
|---|---|
| Main Authors: | , , , , , , , , , , , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society for Clinical Investigation
2014
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4382246/ https://ncbi.nlm.nih.gov/pubmed/25415439 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI75852 |
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