MicroRNA 21 promotes fibrosis of the kidney by silencing metabolic pathways

Scarring of the kidney is a major public health concern, directly promoting loss of kidney function. In order to understand the role of microRNA (miRNA) in the progression of kidney scarring in response to injury, we investigated changes in miRNA expression in two kidney fibrosis models, and identif...

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Hlavní autoři: Chau, B. Nelson, Xin, Cuiyan, Hartner, Jochen, Ren, Shuyu, Castano, Ana P., Linn, Geoffrey, Li, Jian, Tran, Phong T, Kaimal, Vivek, Huang, Xinqiang, Chang, Aaron N, Li, Shenyan, Kalra, Aarti, Grafals, Monica, Portilla, Didier, MacKenna, Deidre A., Orkin, Stuart H., Duffield, Jeremy S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3672221/
https://ncbi.nlm.nih.gov/pubmed/22344686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3003205
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