PGC-1α rescues Huntington’s disease proteotoxicity by preventing oxidative stress and promoting TFEB function

Por Tsunemi, Taiji, Ashe, Travis D., Morrison, Bradley E., Soriano, Kathryn R., Au, Jonathan, Vázquez Roque, Ruben A., Lazarowski, Eduardo R., Damian, Vincent A., Masliah, Eliezer, La Spada, Albert R.
Publicado em 2012

Muscle-specific 4E-BP1 signaling activation improves metabolic parameters during aging and obesity

Por Tsai, Shihyin, Sitzmann, Joanna M., Dastidar, Somasish G., Rodriguez, Ariana A., Vu, Stephanie L., McDonald, Circe E., Academia, Emmeline C., O’Leary, Monique N., Ashe, Travis D., La Spada, Albert R., Kennedy, Brian K.
Publicado no J Clin Invest (2015)

Increased 4E-BP1 expression protects against diet-induced obesity and insulin resistance in male mice

Por Tsai, Shih-Yin, Rodriguez, Ariana A., Dastidar, Somasish G., Del Greco, Elizabeth, Carr, Kaili Lia, Sitzmann, Joanna M., Academia, Emmeline C., Viray, Christian Michael, Martinez, Lizbeth Leon, Kaplowitz, Brian Stephen, Ashe, Travis D., La Spada, Albert R., Kennedy, Brian K.
Publicado no Cell Rep (2016)

Let-7 coordinately suppresses components of the amino acid sensing pathway to repress mTORC1 and induce autophagy

Por Dubinsky, Amy N., Dastidar, Somasish Ghosh, Hsu, Cynthia L., Zahra, Rabaab, Djakovic, Stevan, Duarte, Sonia, Esau, Christine C., Spencer, Brian, Ashe, Travis D., Fischer, Kimberlee M., MacKenna, Deidre A., Sopher, Bryce L., Masliah, Eliezer, Gaasterland, Terry, Chau, B. Nelson, de Almeida, Luis Pereira, Morrison, Bradley E., La Spada, Albert R.
Publicado no Cell Metab (2014)