Silencing Mutant Ataxin-3 Rescues Motor Deficits and Neuropathology in Machado-Joseph Disease Transgenic Mice

Por Nóbrega, Clévio, Nascimento-Ferreira, Isabel, Onofre, Isabel, Albuquerque, David, Hirai, Hirokazu, Déglon, Nicole, de Almeida, Luís Pereira
Publicado em 2013

Caloric restriction stimulates autophagy in rat cortical neurons through neuropeptide Y and ghrelin receptors activation

Por Ferreira-Marques, Marisa, Aveleira, Célia A., Carmo-Silva, Sara, Botelho, Mariana, de Almeida, Luís Pereira, Cavadas, Cláudia
Publicado no Aging (Albany NY) (2016)

Safety profile of the intravenous administration of brain-targeted stable nucleic acid lipid particles

Por Conceição, Mariana, Mendonça, Liliana, Nóbrega, Clévio, Gomes, Célia, Costa, Pedro, Hirai, Hirokazu, Moreira, João Nuno, Lima, Maria C., Manjunath, N., de Almeida, Luís Pereira
Publicado no Data Brief (2016)

Fibroblasts of Machado Joseph Disease patients reveal autophagy impairment

Por Onofre, Isabel, Mendonça, Nuno, Lopes, Sara, Nobre, Rui, de Melo, Joana Barbosa, Carreira, Isabel Marques, Januário, Cristina, Gonçalves, António Freire, de Almeida, Luis Pereira
Publicado no Sci Rep (2016)

Let-7 coordinately suppresses components of the amino acid sensing pathway to repress mTORC1 and induce autophagy

Por Dubinsky, Amy N., Dastidar, Somasish Ghosh, Hsu, Cynthia L., Zahra, Rabaab, Djakovic, Stevan, Duarte, Sonia, Esau, Christine C., Spencer, Brian, Ashe, Travis D., Fischer, Kimberlee M., MacKenna, Deidre A., Sopher, Bryce L., Masliah, Eliezer, Gaasterland, Terry, Chau, B. Nelson, de Almeida, Luis Pereira, Morrison, Bradley E., La Spada, Albert R.
Publicado no Cell Metab (2014)