PGC-1α rescues Huntington’s disease proteotoxicity by preventing oxidative stress and promoting TFEB function

Por Tsunemi, Taiji, Ashe, Travis D., Morrison, Bradley E., Soriano, Kathryn R., Au, Jonathan, Vázquez Roque, Ruben A., Lazarowski, Eduardo R., Damian, Vincent A., Masliah, Eliezer, La Spada, Albert R.
Publicado em 2012

Endocannabinoid hydrolysis generates brain prostaglandins that promote neuroinflammation

Por Nomura, Daniel K., Morrison, Bradley E., Blankman, Jacqueline L., Long, Jonathan Z., Kinsey, Steven G., Marcondes, Maria Cecilia G., Ward, Anna M., Lichtman, Aron H., Conti, Bruno, Cravatt, Benjamin F.
Publicado em 2011

Mutual exacerbation of PGC-1α deregulation and α-synuclein oligomerization

Por Eschbach, Judith, von Einem, Björn, Müller, Kathrin, Bayer, Hanna, Scheffold, Annika, Morrison, Bradley E., Rudolph, K. Lenhard, Thal, Dietmar R., Witting, Anke, Weydt, Patrick, Otto, Markus, Fauler, Michael, Liss, Birgit, McLean, Pamela J., La Spada, Albert R., Ludolph, Albert C., Weishaupt, Jochen H., Danzer, Karin M.
Publicado no Ann Neurol (2014)

Let-7 coordinately suppresses components of the amino acid sensing pathway to repress mTORC1 and induce autophagy

Por Dubinsky, Amy N., Dastidar, Somasish Ghosh, Hsu, Cynthia L., Zahra, Rabaab, Djakovic, Stevan, Duarte, Sonia, Esau, Christine C., Spencer, Brian, Ashe, Travis D., Fischer, Kimberlee M., MacKenna, Deidre A., Sopher, Bryce L., Masliah, Eliezer, Gaasterland, Terry, Chau, B. Nelson, de Almeida, Luis Pereira, Morrison, Bradley E., La Spada, Albert R.
Publicado no Cell Metab (2014)