Metabolic Dysfunction in Pulmonary Hypertension: The Expanding Relevance of the Warburg Effect

Por Cottrill, Katherine A., Chan, Stephen Y.
Publicado em 2013

Investigating pulmonary arterial hypertension from “stem” to stern. Focus on “Identification of a common Wnt-associated genetic signature across multiple cell types in pulmonary ar...

Por Cottrill, Katherine A., Chan, Stephen Y.
Publicado em 2014

Hypoxamirs and Mitochondrial Metabolism

Por Cottrill, Katherine A., Chan, Stephen Y., Loscalzo, Joseph
Publicado em 2014

The MicroRNA-130/301 Family Controls Vasoconstriction in Pulmonary Hypertension

Por Bertero, Thomas, Cottrill, Katherine, Krauszman, Adrienn, Lu, Yu, Annis, Sofia, Hale, Andrew, Bhat, Balkrishen, Waxman, Aaron B., Chau, B. Nelson, Kuebler, Wolfgang M., Chan, Stephen Y.
Publicado no J Biol Chem (2015)

A YAP/TAZ-miR-130/301 molecular circuit exerts systems-level control of fibrosis in a network of human diseases and physiologic conditions

Por Bertero, Thomas, Cottrill, Katherine A., Annis, Sofia, Bhat, Balkrishen, Gochuico, Bernadette R., Osorio, Juan C., Rosas, Ivan, Haley, Kathleen J., Corey, Kathleen E., Chung, Raymond T., Nelson Chau, B., Chan, Stephen Y.
Publicado no Sci Rep (2015)

MicroRNA-21 Integrates Pathogenic Signaling to Control Pulmonary Hypertension: Results of a Network Bioinformatics Approach

Por Parikh, Victoria N., Jin, Richard C., Rabello, Sabrina, Gulbahce, Natali, White, Kevin, Hale, Andrew, Cottrill, Katherine A., Shaik, Rahamthulla S., Waxman, Aaron B., Zhang, Ying-Yi, Maron, Bradley A., Hartner, Jochen C., Fujiwara, Yuko, Orkin, Stuart H., Haley, Kathleen J., Barabási, Albert-László, Loscalzo, Joseph, Chan, Stephen Y.
Publicado em 2012

Systems-level regulation of microRNA networks by miR-130/301 promotes pulmonary hypertension

Por Bertero, Thomas, Lu, Yu, Annis, Sofia, Hale, Andrew, Bhat, Balkrishen, Saggar, Rajan, Saggar, Rajeev, Wallace, W. Dean, Ross, David J., Vargas, Sara O., Graham, Brian B., Kumar, Rahul, Black, Stephen M., Fratz, Sohrab, Fineman, Jeffrey R., West, James D., Haley, Kathleen J., Waxman, Aaron B., Chau, B. Nelson, Cottrill, Katherine A., Chan, Stephen Y.
Publicado em 2014

Matrix remodeling promotes pulmonary hypertension through feedback mechanoactivation of the YAP/TAZ-miR-130/301 circuit

Por Bertero, Thomas, Cottrill, Katherine A., Lu, Yu, Haeger, Christina M., Dieffenbach, Paul, Annis, Sofia, Hale, Andrew, Bhat, Balkrishen, Kaimal, Vivek, Zhang, Ying-Yi, Graham, Brian B., Kumar, Rahul, Saggar, Rajan, Saggar, Rajeev, Wallace, W. Dean, Ross, David J., Black, Stephen M., Fratz, Sohrab, Fineman, Jeffrey R., Vargas, Sara O., Haley, Kathleen J., Waxman, Aaron B., Chau, B. Nelson, Fredenburgh, Laura E., Chan, Stephen Y.
Publicado no Cell Rep (2015)

Vascular stiffness mechanoactivates YAP/TAZ-dependent glutaminolysis to drive pulmonary hypertension

Por Bertero, Thomas, Oldham, William M., Cottrill, Katherine A., Pisano, Sabrina, Vanderpool, Rebecca R., Yu, Qiujun, Zhao, Jingsi, Tai, Yiyin, Tang, Ying, Zhang, Ying-Yi, Rehman, Sofiya, Sugahara, Masataka, Qi, Zhi, Gorcsan, John, Vargas, Sara O., Saggar, Rajan, Saggar, Rajeev, Wallace, W. Dean, Ross, David J., Haley, Kathleen J., Waxman, Aaron B., Parikh, Victoria N., De Marco, Teresa, Hsue, Priscilla Y., Morris, Alison, Simon, Marc A., Norris, Karen A., Gaggioli, Cedric, Loscalzo, Joseph, Fessel, Joshua, Chan, Stephen Y.
Publicado no J Clin Invest (2016)