A YAP/TAZ-miR-130/301 molecular circuit exerts systems-level control of fibrosis in a network of human diseases and physiologic conditions

The molecular origins of fibrosis affecting multiple tissue beds remain incompletely defined. Previously, we delineated the critical role of the control of extracellular matrix (ECM) stiffening by the mechanosensitive microRNA-130/301 family, as activated by the YAP/TAZ co-transcription factors, in...

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Bibliografische gegevens
Gepubliceerd in:Sci Rep
Hoofdauteurs: Bertero, Thomas, Cottrill, Katherine A., Annis, Sofia, Bhat, Balkrishen, Gochuico, Bernadette R., Osorio, Juan C., Rosas, Ivan, Haley, Kathleen J., Corey, Kathleen E., Chung, Raymond T., Nelson Chau, B., Chan, Stephen Y.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2015
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4678880/
https://ncbi.nlm.nih.gov/pubmed/26667495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep18277
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