MicroRNA-21 Integrates Pathogenic Signaling to Control Pulmonary Hypertension: Results of a Network Bioinformatics Approach

BACKGROUND: Pulmonary hypertension (PH) is driven by diverse pathogenic etiologies. Owing to their pleiotropic actions, microRNA (miRNA) are potential candidates for coordinated regulation of these disease stimuli. METHODS AND RESULTS: Using a network biology approach, we identify miRNA associated w...

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Detalhes bibliográficos
Main Authors: Parikh, Victoria N., Jin, Richard C., Rabello, Sabrina, Gulbahce, Natali, White, Kevin, Hale, Andrew, Cottrill, Katherine A., Shaik, Rahamthulla S., Waxman, Aaron B., Zhang, Ying-Yi, Maron, Bradley A., Hartner, Jochen C., Fujiwara, Yuko, Orkin, Stuart H., Haley, Kathleen J., Barabási, Albert-László, Loscalzo, Joseph, Chan, Stephen Y.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3353408/
https://ncbi.nlm.nih.gov/pubmed/22371328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.111.060269
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