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Anti-miRs Competitively Inhibit microRNAs in Argonaute Complexes
MicroRNAs (miRNAs), small RNA molecules that post-transcriptionally regulate mRNA expression, are crucial in diverse developmental and physiological programs and their misregulation can lead to disease. Chemically modified oligonucleotides have been developed to modulate miRNA activity for therapeut...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4084633/ https://ncbi.nlm.nih.gov/pubmed/24992387 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0100951 |
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