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Anti-miRs Competitively Inhibit microRNAs in Argonaute Complexes

MicroRNAs (miRNAs), small RNA molecules that post-transcriptionally regulate mRNA expression, are crucial in diverse developmental and physiological programs and their misregulation can lead to disease. Chemically modified oligonucleotides have been developed to modulate miRNA activity for therapeut...

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Detalles Bibliográficos
Main Authors: Hogan, Daniel J., Vincent, Thomas M., Fish, Sarah, Marcusson, Eric G., Bhat, Balkrishen, Chau, B. Nelson, Zisoulis, Dimitrios G.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4084633/
https://ncbi.nlm.nih.gov/pubmed/24992387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0100951
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