Secondary mechanisms of diversification in the human antibody repertoire

Por Briney, Bryan S., Jr., James E. Crowe
Publicado em 2013

Human Peripheral Blood Antibodies with Long HCDR3s Are Established Primarily at Original Recombination Using a Limited Subset of Germline Genes

Por Briney, Bryan S., Willis, Jordan R., Crowe, James E.
Publicado em 2012

Location and length distribution of somatic hypermutation-associated DNA insertions and deletions reveals regions of antibody structural plasticity

Por Briney, Bryan S., Willis, Jordan R., Crowe, James E.
Publicado em 2012

Clonify: unseeded antibody lineage assignment from next-generation sequencing data

Por Briney, Bryan, Le, Khoa, Zhu, Jiang, Burton, Dennis R.
Publicado no Sci Rep (2016)

Frequency and genetic characterization of V(DD)J recombinants in the human peripheral blood antibody repertoire

Por Briney, Bryan S, Willis, Jordan R, Hicar, Mark D, Thomas, James W, Crowe, James E
Publicado em 2012

Human Germline Antibody Gene Segments Encode Polyspecific Antibodies

Por Willis, Jordan R., Briney, Bryan S., DeLuca, Samuel L., Crowe, James E., Meiler, Jens
Publicado em 2013

Tissue-Specific Expressed Antibody Variable Gene Repertoires

Por Briney, Bryan S., Willis, Jordan R., Finn, Jessica A., McKinney, Brett A., Crowe, James E.
Publicado em 2014

Pseudovirion Particles Bearing Native HIV Envelope Trimers Facilitate a Novel Method for Generating Human Neutralizing Monoclonal Antibodies against HIV

Por Hicar, Mark D., Chen, Xuemin, Briney, Bryan, Hammonds, Jason, Wang, Jaang-Jiun, Kalams, Spyros, Spearman, Paul W., Crowe, James E.
Publicado em 2010

Epitope-specific human influenza antibody repertoires diversify by B cell intraclonal sequence divergence and interclonal convergence()

Por Krause, Jens C., Tsibane, Tshidi, Tumpey, Terrence M., Huffman, Chelsey J., Briney, Bryan S., Smith, Scott A., Basler, Christopher F., Crowe, James E.
Publicado em 2011

Identification of common features in prototype broadly neutralizing antibodies to HIV envelope V2 apex to facilitate vaccine design

Por Andrabi, Raiees, Voss, James E, Liang, Chi-Hui, Briney, Bryan, McCoy, Laura E, Wu, Chung-Yi, Wong, Chi-Huey, Poignard, Pascal, Burton, Dennis R.
Publicado no Immunity (2015)

Long antibody HCDR3s from HIV-naïve donors presented on a PG9 neutralizing antibody background mediate HIV neutralization

Por Willis, Jordan R., Finn, Jessica A., Briney, Bryan, Sapparapu, Gopal, Singh, Vidisha, King, Hannah, LaBranche, Celia C., Montefiori, David C., Meiler, Jens, Crowe, James E.
Publicado no Proc Natl Acad Sci U S A (2016)

Human Antibodies that Recognize Novel Immunodominant Quaternary Epitopes on the HIV-1 Env Protein

Por Hicar, Mark D., Chen, Xuemin, Sulli, Chidananda, Barnes, Trevor, Goodman, Jason, Sojar, Hakimuddin, Briney, Bryan, Willis, Jordan, Chukwuma, Valentine U., Kalams, Spyros A., Doranz, Benjamin J., Spearman, Paul, Crowe, James E.
Publicado no PLoS One (2016)

Haplotype-Phased Synthetic Long Reads from Short-Read Sequencing

Por Stapleton, James A., Kim, Jeongwoon, Hamilton, John P., Wu, Ming, Irber, Luiz C., Maddamsetti, Rohan, Briney, Bryan, Newton, Linsey, Burton, Dennis R., Brown, C. Titus, Chan, Christina, Buell, C. Robin, Whitehead, Timothy A.
Publicado no PLoS One (2016)

Promiscuous glycan site recognition by antibodies to the high-mannose patch of gp120 broadens neutralization of HIV

Por Sok, Devin, Doores, Katie J., Briney, Bryan, Le, Khoa M., Saye-Francisco, Karen F., Ramos, Alejandra, Kulp, Daniel W., Julien, Jean-Philippe, Menis, Sergey, Wickramasinghe, Lalinda, Seaman, Michael S., Schief, William R., Wilson, Ian A., Poignard, Pascal, Burton, Dennis R.
Publicado em 2014

Priming a broadly neutralizing antibody response to HIV-1 using a germline-targeting immunogen

Por Jardine, Joseph G., Ota, Takayuki, Sok, Devin, Pauthner, Matthias, Kulp, Daniel W., Kalyuzhniy, Oleksandr, Skog, Patrick D., Thinnes, Theresa C., Bhullar, Deepika, Briney, Bryan, Menis, Sergey, Jones, Meaghan, Kubitz, Mike, Spencer, Skye, Adachi, Yumiko, Burton, Dennis R., Schief, William R., Nemazee, David
Publicado no Science (2015)

Recombinant HIV envelope trimer selects for quaternary-dependent antibodies targeting the trimer apex

Por Sok, Devin, van Gils, Marit J., Pauthner, Matthias, Julien, Jean-Philippe, Saye-Francisco, Karen L., Hsueh, Jessica, Briney, Bryan, Lee, Jeong Hyun, Le, Khoa M., Lee, Peter S., Hua, Yuanzi, Seaman, Michael S., Moore, John P., Ward, Andrew B., Wilson, Ian A., Sanders, Rogier W., Burton, Dennis R.
Publicado no Proc Natl Acad Sci U S A (2014)

Priming HIV-1 broadly neutralizing antibody precursors in human Ig loci transgenic mice

Por Sok, Devin, Briney, Bryan, Jardine, Joseph G., Kulp, Daniel W., Menis, Sergey, Pauthner, Matthias, Wood, Andrew, Lee, E-Chiang, Le, Khoa M., Jones, Meaghan, Ramos, Alejandra, Kalyuzhniy, Oleksandr, Adachi, Yumiko, Kubitz, Michael, MacPherson, Skye, Bradley, Allan, Friedrich, Glenn A., Schief, William R., Burton, Dennis R.
Publicado no Science (2016)

Holes in the glycan shield of the native HIV envelope are a target of trimer-elicited neutralizing antibodies

Por McCoy, Laura E, van Gils, Marit J, Ozorowski, Gabriel, Messmer, Terrence, Briney, Bryan, Voss, James E, Kulp, Daniel W, Macauley, Matthew S, Sok, Devin, Pauthner, Matthias, Menis, Sergey, Cottrell, Christopher A, Torres, Jonathan L, Hsueh, Jessica, Schief, William R, Wilson, Ian A, Ward, Andrew B, Sanders, Rogier W, Burton, Dennis R
Publicado no Cell Rep (2016)

Early Antibody Lineage Diversification and Independent Limb Maturation Lead to Broad HIV-1 Neutralization Targeting the Env High-Mannose Patch

Por MacLeod, Daniel T., Choi, Nancy M., Briney, Bryan, Garces, Fernando, Ver, Lorena S., Landais, Elise, Murrell, Ben, Wrin, Terri, Kilembe, William, Liang, Chi-Hui, Ramos, Alejandra, Bian, Chaoran B., Wickramasinghe, Lalinda, Kong, Leopold, Eren, Kemal, Wu, Chung-Yi, Wong, Chi-Huey, Kosakovsky Pond, Sergei L., Wilson, Ian A., Burton, Dennis R., Poignard, Pascal
Publicado no Immunity (2016)

HIV-1 broadly neutralizing antibody precursor B cells revealed by germline-targeting immunogen

Por Jardine, Joseph G., Kulp, Daniel W., Havenar-Daughton, Colin, Sarkar, Anita, Briney, Bryan, Sok, Devin, Sesterhenn, Fabian, Ereño-Orbea, June, Kalyuzhniy, Oleksandr, Deresa, Isaiah, Hu, Xiaozhen, Spencer, Skye, Jones, Meaghan, Georgeson, Erik, Adachi, Yumiko, Kubitz, Michael, deCamp, Allan C., Julien, Jean-Philippe, Wilson, Ian A., Burton, Dennis R., Crotty, Shane, Schief, William R.
Publicado no Science (2016)