Human Peripheral Blood Antibodies with Long HCDR3s Are Established Primarily at Original Recombination Using a Limited Subset of Germline Genes

A number of antibodies that efficiently neutralize microbial targets contain long heavy chain complementarity determining region 3 (HCDR3) loops. For HIV, several of the most broad and potently neutralizing antibodies have exceptionally long HCDR3s. Two broad potently neutralizing HIV-specific antib...

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Detaylı Bibliyografya
Asıl Yazarlar: Briney, Bryan S., Willis, Jordan R., Crowe, James E.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2012
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3348910/
https://ncbi.nlm.nih.gov/pubmed/22590602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0036750
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