Haplotype-Phased Synthetic Long Reads from Short-Read Sequencing

Next-generation DNA sequencing has revolutionized the study of biology. However, the short read lengths of the dominant instruments complicate assembly of complex genomes and haplotype phasing of mixtures of similar sequences. Here we demonstrate a method to reconstruct the sequences of individual n...

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Bibliographic Details
Published in:PLoS One
Main Authors: Stapleton, James A., Kim, Jeongwoon, Hamilton, John P., Wu, Ming, Irber, Luiz C., Maddamsetti, Rohan, Briney, Bryan, Newton, Linsey, Burton, Dennis R., Brown, C. Titus, Chan, Christina, Buell, C. Robin, Whitehead, Timothy A.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2016
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4720449/
https://ncbi.nlm.nih.gov/pubmed/26789840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0147229
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