Haplotype-Phased Synthetic Long Reads from Short-Read Sequencing

Next-generation DNA sequencing has revolutionized the study of biology. However, the short read lengths of the dominant instruments complicate assembly of complex genomes and haplotype phasing of mixtures of similar sequences. Here we demonstrate a method to reconstruct the sequences of individual n...

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Publicat a:PLoS One
Autors principals: Stapleton, James A., Kim, Jeongwoon, Hamilton, John P., Wu, Ming, Irber, Luiz C., Maddamsetti, Rohan, Briney, Bryan, Newton, Linsey, Burton, Dennis R., Brown, C. Titus, Chan, Christina, Buell, C. Robin, Whitehead, Timothy A.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2016
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4720449/
https://ncbi.nlm.nih.gov/pubmed/26789840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0147229
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