Haplotype-Phased Synthetic Long Reads from Short-Read Sequencing

Next-generation DNA sequencing has revolutionized the study of biology. However, the short read lengths of the dominant instruments complicate assembly of complex genomes and haplotype phasing of mixtures of similar sequences. Here we demonstrate a method to reconstruct the sequences of individual n...

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Veröffentlicht in:PLoS One
Hauptverfasser: Stapleton, James A., Kim, Jeongwoon, Hamilton, John P., Wu, Ming, Irber, Luiz C., Maddamsetti, Rohan, Briney, Bryan, Newton, Linsey, Burton, Dennis R., Brown, C. Titus, Chan, Christina, Buell, C. Robin, Whitehead, Timothy A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2016
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4720449/
https://ncbi.nlm.nih.gov/pubmed/26789840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0147229
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