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Comparisons of the antibody repertoires of a humanized rodent and humans by high throughput sequencing

The humanization of animal model immune systems by genetic engineering has shown great promise for antibody discovery, tolerance studies and for the evaluation of vaccines. Assessment of the baseline antibody repertoires of unimmunized model animals will be useful as a benchmark for future immunizat...

詳細記述

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書誌詳細
出版年:Sci Rep
主要な著者: Joyce, Collin, Burton, Dennis R., Briney, Bryan
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6981180/
https://ncbi.nlm.nih.gov/pubmed/31980672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-57764-7
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