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Comparisons of the antibody repertoires of a humanized rodent and humans by high throughput sequencing

The humanization of animal model immune systems by genetic engineering has shown great promise for antibody discovery, tolerance studies and for the evaluation of vaccines. Assessment of the baseline antibody repertoires of unimmunized model animals will be useful as a benchmark for future immunizat...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Joyce, Collin, Burton, Dennis R., Briney, Bryan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6981180/
https://ncbi.nlm.nih.gov/pubmed/31980672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-57764-7
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