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High-throughput Sequencing of the Zebrafish Antibody Repertoire

Despite tremendous progress in understanding the nature of the immune system, the full diversity of an organism’s antibody repertoire is unknown. We used high-throughput sequencing of the variable domain of the antibody heavy chain from 14 zebrafish to analyze VDJ usage and antibody sequence. Zebraf...

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Detalhes bibliográficos
Main Authors: Weinstein, Joshua A., Jiang, Ning, White, Richard A., Fisher, Daniel S., Quake, Stephen R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3086368/
https://ncbi.nlm.nih.gov/pubmed/19423829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1170020
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