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Determinism and stochasticity during maturation of the zebrafish antibody repertoire
It is thought that the adaptive immune system of immature organisms follows a more deterministic program of antibody creation than is found in adults. We used high-throughput sequencing to characterize the diversifying antibody repertoire in zebrafish over five developmental time points. We found th...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3069157/ https://ncbi.nlm.nih.gov/pubmed/21393572 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1014277108 |
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