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Comparisons of the antibody repertoires of a humanized rodent and humans by high throughput sequencing

The humanization of animal model immune systems by genetic engineering has shown great promise for antibody discovery, tolerance studies and for the evaluation of vaccines. Assessment of the baseline antibody repertoires of unimmunized model animals will be useful as a benchmark for future immunizat...

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Библиографические подробности
Опубликовано в: :Sci Rep
Главные авторы: Joyce, Collin, Burton, Dennis R., Briney, Bryan
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2020
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6981180/
https://ncbi.nlm.nih.gov/pubmed/31980672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-57764-7
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