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Joint haplotype phasing and genotype calling of multiple individuals using haplotype informative reads
Motivation: Hidden Markov model, based on Li and Stephens model that takes into account chromosome sharing of multiple individuals, results in mainstream haplotype phasing algorithms for genotyping arrays and next-generation sequencing (NGS) data. However, existing methods based on this model assume...
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Oxford University Press
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3777110/ https://ncbi.nlm.nih.gov/pubmed/23943637 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btt418 |
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