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Joint haplotype assembly and genotype calling via sequential Monte Carlo algorithm

BACKGROUND: Genetic variations predispose individuals to hereditary diseases, play important role in the development of complex diseases, and impact drug metabolism. The full information about the DNA variations in the genome of an individual is given by haplotypes, the ordered lists of single nucle...

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Publicado en:BMC Bioinformatics
Autores principales: Ahn, Soyeon, Vikalo, Haris
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4503296/
https://ncbi.nlm.nih.gov/pubmed/26178880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-015-0651-8
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