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Joint haplotype assembly and genotype calling via sequential Monte Carlo algorithm

BACKGROUND: Genetic variations predispose individuals to hereditary diseases, play important role in the development of complex diseases, and impact drug metabolism. The full information about the DNA variations in the genome of an individual is given by haplotypes, the ordered lists of single nucle...

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Bibliografski detalji
Izdano u:BMC Bioinformatics
Glavni autori: Ahn, Soyeon, Vikalo, Haris
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4503296/
https://ncbi.nlm.nih.gov/pubmed/26178880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-015-0651-8
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