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Joint haplotype assembly and genotype calling via sequential Monte Carlo algorithm

BACKGROUND: Genetic variations predispose individuals to hereditary diseases, play important role in the development of complex diseases, and impact drug metabolism. The full information about the DNA variations in the genome of an individual is given by haplotypes, the ordered lists of single nucle...

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Bibliografische gegevens
Gepubliceerd in:BMC Bioinformatics
Hoofdauteurs: Ahn, Soyeon, Vikalo, Haris
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2015
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4503296/
https://ncbi.nlm.nih.gov/pubmed/26178880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-015-0651-8
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