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Genotype calling from next-generation sequencing data using haplotype information of reads
Motivation: Low coverage sequencing provides an economic strategy for whole genome sequencing. When sequencing a set of individuals, genotype calling can be challenging due to low sequencing coverage. Linkage disequilibrium (LD) based refinement of genotyping calling is essential to improve the accu...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Oxford University Press
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3493122/ https://ncbi.nlm.nih.gov/pubmed/22285565 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bts047 |
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