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Genotype calling from next-generation sequencing data using haplotype information of reads

Motivation: Low coverage sequencing provides an economic strategy for whole genome sequencing. When sequencing a set of individuals, genotype calling can be challenging due to low sequencing coverage. Linkage disequilibrium (LD) based refinement of genotyping calling is essential to improve the accu...

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Bibliografiska uppgifter
Huvudupphovsmän: Zhi, Degui, Wu, Jihua, Liu, Nianjun, Zhang, Kui
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2012
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3493122/
https://ncbi.nlm.nih.gov/pubmed/22285565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bts047
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