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Calling amplified haplotypes in next generation tumor sequence data

During tumor initiation and progression, cancer cells acquire a selective advantage, allowing them to outcompete their normal counterparts. Identification of the genetic changes that underlie these tumor acquired traits can provide deeper insights into the biology of tumorigenesis. Regions of copy n...

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Bibliografiske detaljer
Main Authors: Dewal, Ninad, Hu, Yang, Freedman, Matthew L., LaFramboise, Thomas, Pe'er, Itsik
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3266043/
https://ncbi.nlm.nih.gov/pubmed/22090379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.122564.111
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