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Accurate estimation of short read mapping quality for next-generation genome sequencing

Motivation: Several software tools specialize in the alignment of short next-generation sequencing reads to a reference sequence. Some of these tools report a mapping quality score for each alignment—in principle, this quality score tells researchers the likelihood that the alignment is correct. How...

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Main Authors: Ruffalo, Matthew, Koyutürk, Mehmet, Ray, Soumya, LaFramboise, Thomas
格式: Artigo
語言:Inglês
出版: Oxford University Press 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3436835/
https://ncbi.nlm.nih.gov/pubmed/22962451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bts408
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