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Allelic Selection of Amplicons in Glioblastoma Revealed by Combining Somatic and Germline Analysis

Cancer is a disease driven by a combination of inherited risk alleles coupled with the acquisition of somatic mutations, including amplification and deletion of genomic DNA. Potential relationships between the inherited and somatic aspects of the disease have only rarely been examined on a genome-wi...

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Autori principali: LaFramboise, Thomas, Dewal, Ninad, Wilkins, Katherine, Pe'er, Itsik, Freedman, Matthew L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2932683/
https://ncbi.nlm.nih.gov/pubmed/20824129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1001086
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