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Allelic Selection of Amplicons in Glioblastoma Revealed by Combining Somatic and Germline Analysis

Cancer is a disease driven by a combination of inherited risk alleles coupled with the acquisition of somatic mutations, including amplification and deletion of genomic DNA. Potential relationships between the inherited and somatic aspects of the disease have only rarely been examined on a genome-wi...

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Detalhes bibliográficos
Main Authors: LaFramboise, Thomas, Dewal, Ninad, Wilkins, Katherine, Pe'er, Itsik, Freedman, Matthew L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2932683/
https://ncbi.nlm.nih.gov/pubmed/20824129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1001086
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